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Research Relating to Transgender HRT

Mutual Medical Education for a Neglected Community

While there is a plethora of research on trans people, the focus of this repository is Gender Affirming HRT (Hormone Replacement Therapy). There is a section on affirming surgical procedures that will grow with time (and hopefully your help!), but the bulk of the research posted here will focus on the use of testosterones, estrogens, antiandrogens, progestogens, and puberty blockers (GnRH agonists).

Categories & How to Use Them

The research is divided into categories, but it's important to note that it's NOT divided by transition type or gender identity, with the exception of a special category for research that mentions non-binary folks. It hasn't been divided between trans masculine and trans feminine because many of the studies involve both and much of the research relating to the effects of testosterone and estrogen applies to both groups in opposing ways. If you are trans feminine and looking for information about the effects of going on estrogen, it's strongly encouraged that you also read the research about testosterone so you are aware of what effects you'll be losing when you start antiandrogens. The inverse applies for transmasculine folks as well. Some research appears in multiple categories as applicable, and the newest posted research will appear at the top of each category.

 

Paywalls

Some of these research papers are behind paywalls, meaning they are not free to read in their entirety. Reading the abstract can often give some valuable insight, and if you are a college student or work in medicine you may be able to access the full text version without paying. If this site indicates there is NOT a paywall, but you don't see the full article when you follow the link, look for a "Download" link- that will download the full article to your device as a PDF. Some of the sites have a link that allows you to request the full version from the author, which often works as authors want their work to be read. The creators of this site firmly believe all research papers should be free to the public, but unfortunately academia and the scientific community are drenched in accessibility and class barriers. Great effort was put into locating free, full-text versions and the only ones behind paywalls could not be located elsewhere for free. If you find a link to a free, full-text version of a paper that is listed here behind a paywall, please submit it using the Submit a Link form so others can access it.

 

Not All Research is Equal

 

There are different types of research papers, ranging from studies of a single case to systematic reviews of all literature available on a topic. Research posted here is not necessarily hard fact, or even promoted as truth by the creators of this site. In fact, you may find some of it downright offensive, especially in regard to terminology used. Some of it is contradicted by other research posted here. The information is presented as-is, without opinion, for you to use how you see fit. 
Here is a graphic that may help those who are new to research papers determine how much weight a single piece of research may have based on what type of paper it is:

study_design_v3.0.png

Ways to Use This Research

If you have concerns that are backed up by research found here, print it out and take it to your doctor or healthcare provider. They may be able to help you understand what it means and/or it may be new information for them that ends up helping you and other trans folks. 

Take it all in, and keep it in mind as you start your HRT journey. If something happens to you that you read about here, having the knowledge of why it's happening may be extremely helpful. 

 

Prepare yourself for possibilities.

 

Consider the risks before you decide what steps you want to take in your transition. There are risks and rewards for everything, and only you can decide if it's worth it in your particular case.

If you have a loved one on HRT or considering it, educate yourself on what they may be experiencing.

Share this repository with friends, family, medical professionals, etc to increase general knowledge about transgender HRT!

Read about why this repository was created

Title
Paywall
Date published
Date Added
Considerations for the Use of Minimally Invasive Aesthetic Procedures for Facial Remodeling in Transgender Individuals
No
5/13/2021
9/21/2022
Longitudinal Cohort Study of Gender Affirmation and HIV-Related Health in Transgender and Gender Diverse Adults: The LEGACY Project Protocol
No
3/1/2021
9/21/2022
Transgender and Gender-nonbinary Patient Satisfaction after Transmasculine Chest Surgery
No
3/1/2021
9/21/2022
Psychosocial Differences Between Transgender Individuals With and Without History of Nonsurgical Facial Injectables
No
1/1/2021
9/21/2022
Double Incision Mastectomy with Free Nipple Graft for Masculinizing Chest Wall Surgery
No
11/1/2020
9/21/2022
Applying concurrent multidisciplinary care to gender affirmation in transgender women: A case series
No
7/29/2020
9/21/2022
The outcomes of the radial artery forearm free-flap phalloplasty in transgender men: A focus on surgical technique and flap vascular complications
No
10/1/2020
9/21/2022
Gender Affirming Body Contouring and Physical Transformation in Transgender Individuals
No
4/1/2022
9/21/2022
From Anatomical Modifications to Skin Quality: Case Series of Botulinum Toxin and Facial Fillers for Facial Feminization in Transgender Women
No
4/2/2022
9/21/2022
Feasibility of an External Erectile Prosthesis for Transgender Men Who have Undergone Phalloplasty
No
10/1/2022
9/21/2022
A Proposed Inventory to Assess Changes in Orgasm Function of Transgender Patients Following Gender Affirming Treatments: Pilot Study
No
6/1/2022
9/21/2022
Examining Chest Femininity of Hormone Treated Vs. Surgically Augmented Transgender Women
No
6/1/2022
9/21/2022
Reducing Partial Nipple Graft Necrosis Following Masculinizing Chest Reconstruction with Negative Pressure Wound Therapy
No
6/1/2022
9/21/2022
A SINGLE SURGEON RETROSPECTIVE REVIEW OF CHEST MASCULINIZATION SURGERY IN TRANSGENDER AND NON-BINARY ADOLESCENTS AND YOUNG ADULTS
No
4/1/2022
9/21/2022
COMPARISON OF CHEST FEMININITY OF TRANSGENDER WOMEN WITH HORMONE TREATMENT VS. SURGICALLY AUGMENTED WITH BREAST IMPLANTS
No
4/1/2022
9/21/2022
UNDER THE MICROSCOPE: A LOOK AT RELATIVE RISK OF MALIGNANCY IN TRANSGENDER MASTECTOMY
No
4/1/2022
9/21/2022
A Comparative Study of Urinary Complication Rates before and after the Incorporation of a Urethral Lengthening Technique during Masculinizing Genital Gender Affirmation Surgery
No
4/1/2022
9/21/2022
Penile Prosthesis in Transgender Men after Phalloplasty
No
4/1/2022
9/21/2022
Penile Flap Inversion Vaginoplasty in Transgender Women: Contemporary Morbidity and Learning-Curve Analysis From a High-Volume Reconstructive Center
No
2/23/2022
9/21/2022
BRCA Mutations and the Implications in Transgender Individuals Undergoing Top Surgery: An Operative Dilemma
No
1/1/2022
9/21/2022
Sexual Well-Being in Transgender Patients: Could Gender Confirming-Chest Surgery Be Enough?
No
1/1/2022
9/21/2022
Squamous Cell Carcinoma in a Transgender Man's Neo-Urethra after Metoidioplasty
No
12/1/2020
9/21/2022
Perineal Cyst in Transgender Men: A Rare Complication Following Gender Affirming Surgery – A Case Series and Literature Overview
No
10/1/2021
9/21/2022
Feasibility, Safety, and Satisfaction of Combined Hysterectomy with Bilateral Salpingo-Oophorectomy and Chest Surgery in Transgender and Gender Non-Conforming Individuals
No
6/29/2021
9/21/2022
Flap Selection Algorithm Based on the Body Mass Index for Phalloplasty in Female-to-Male Transgender: Techniques and Outcomes
No
7/1/2021
9/21/2022
Risk factors for genital lichen sclerosus in men
Yes
10/1/2010
4/21/2020
Medical dermatologic conditions in transgender women
No
10/11/2018
4/21/2020
Gender-affirming hormones and surgery in transgender children and adolescents
No
6/1/2019
4/20/2020
Transwomen and the Metabolic Syndrome: Is Orchiectomy Protective?
No
8/1/2016
4/20/2020
Sexual Functioning in Transsexuals Following Hormone Therapy and Genital Surgery: A Review (CME)
No
11/01/2009
4/20/2020
Sexual and Physical Health After Sex Reassignment Surgery
No
12/1/2005
4/20/2020
Sexual Desire in Trans Persons: Associations with SexReassignment Treatment
No
1/1/2014
4/20/2020
A Prospective Study on Sexual Function and Mood in Female-to-Male Transsexuals During Testosterone Administration and After Sex Reassignment Surgery
No
3/7/2013
4/20/2020
Orgasm in the postoperative transsexual
Yes
4/1/1993
4/20/2020
Long-Term Sensitivity and Patient-Reported Functionality of the Neoclitoris After Gender Reassignment Surgery
Yes
2/1/2017
4/20/2020
Endometriosis Presenting in a Transgender Male
Yes
11/1/2017
4/20/2020
Factors Associated with Gender-Affirming Surgery and Age of Hormone Therapy Initiation Among Transgender Adults
No
10/1/2017
4/20/2020
Reduction in Mental Health Treatment Utilization Among Transgender Individuals After Gender-Affirming Surgeries: A Total Population Study
No
10/4/2019
4/20/2020
Healthcare costs and quality of life outcomes following gender affirming surgery in trans men: a review
No
10/9/2017
4/20/2020
Vaginal prolapse, pelvic floor function, and related symptoms 16 years after sex reassignment surgery in transsexuals
Yes
4/1/2011
4/20/2020
Long-Term Urogynecological Complications after Sex Reassignment Surgery in Transsexual Patients: a Retrospective Study of 44 Patients and Diagnostic Algorithm Proposal -
No
12/15/2017
4/20/2020
Transgender Phonosurgery: A Systematic Review and Meta-analysis
Yes
3/28/2017
4/20/2020
Vocal Feminization for Transgender Women: Current Strategies and Patient Perspectives
No
2/12/2020
4/20/2020
Surgical and pharmacological reassignment: influence on transsexual cardiovascular risk profile
Yes
8/1/2017
4/20/2020
Anterior Glottic Web Formation for Voice Feminization: Experience of 27 Patients
Yes
3/31/2017
4/20/2020
Uterus transplantation in and beyond cisgender women: revisiting procreative liberty in light of emerging reproductive technologies
No
7/10/2018
4/20/2020
Occurence of phantom genitalia after gender reassignment surgery
Yes
2/1/2007
4/20/2020
Phantom penises in transsexuals.
Yes
1/1/2008
4/20/2020
Phantom erectile penis after sex reassignment surgery.
Yes
1/1/2008
4/20/2020
Female-to-male transgender chest reconstruction: A large consecutive, single-surgeon experience
Yes
12/1/2011
4/20/2020
Chest Reconstruction and Chest Dysphoria in Transmasculine Minors and Young Adults
No
5/1/2018
4/20/2020
Sexual Function After Shallow and Full-Depth Vaginoplasty: Challenges, Clinical Findings, and Treatment Strategies- Urologic Perspectives
Yes
7/1/2018
4/20/2020

AFFIRMING PROCEDURES

AGING

APPETITE & WEIGHT

BEHAVIORAL CHANGES

BONE HEALTH

Title
Paywall
Date published
Date Added
Testosterone in men with hypogonadism and transgender males: a systematic review comparing three different preparations
No
7/25/2022
9/21/2022
Bone health in transgender people: a narrative review
No
5/27/2022
9/21/2022
Bone Safety During the First Ten Years of Gender‐Affirming Hormonal Treatment in Transwomen and Transmen
No
12/7/2018
4/26/2020
Effect of pubertal suppression and cross-sex hormone therapy on bone turnover markers and bone mineral apparent density (BMAD) in transgender adolescents
No
11/11/2016
4/20/2020
Bone Mass in Young Adulthood Following Gonadotropin-Releasing Hormone Analog Treatment and Cross-Sex Hormone Treatment in Adolescents With Gender Dysphoria
No
2/1/2015
4/20/2020
Transgender bone health
Yes
5/14/2019
4/20/2020
Systematic Review of the Long-Term Effects of Transgender Hormone Therapy on Bone Markers and Bone Mineral Density and Their Potential Effects in Implant Therapy
No
6/1/2019
4/20/2020
Osteoporosis and Bone Health in Transgender Persons
Yes
6/1/2019
4/20/2020
Bone Health in the Transgender Population
Yes
7/1/2019
4/20/2020
Body composition, bone turnover, and bone mass in trans men during testosterone treatment: 1-year follow-up data from a prospective case–controlled study (ENIGI)
No
2/1/2015
4/20/2020
Effect of Sex Steroids on the Bone Health of Transgender Individuals: A Systematic Review and Meta-Analysis
No
9/13/2017
4/20/2020
Cortical and trabecular bone mineral density in transsexuals after long-term cross-sex hormonal treatment: A cross-sectional study
Yes
8/1/2015
4/20/2020

CANCER

Title
Paywall
Date published
Date Added
Serous Borderline Tumor in Transgender Female-to-Male Individuals: A Case Report of Androgen Receptor-Positive Ovarian Cancer
No
6/7/2021
9/21/2022
BRCA2-associated Breast Cancer in Transgender Women: Reconstructive Challenges and Literature Review
No
4/1/2022
9/21/2022
UNDER THE MICROSCOPE: A LOOK AT RELATIVE RISK OF MALIGNANCY IN TRANSGENDER MASTECTOMY
No
4/1/2022
9/21/2022
BRCA Mutations and the Implications in Transgender Individuals Undergoing Top Surgery: An Operative Dilemma
No
1/1/2022
9/21/2022
Squamous Cell Carcinoma in a Transgender Man's Neo-Urethra after Metoidioplasty
No
12/1/2020
9/21/2022
A rare case of breast cancer in a transgender woman
No
11/1/2021
9/21/2022
Effects of testosterone treatment on transgender males: A single-institution study
No
10/10/2021
9/21/2022
Prevalence of cardiovascular disease and cancer during cross-sex hormone therapy in a large cohort of trans persons: a case–control study
No
9/13/2013
4/20/2020
Effects of hormones and hormone therapy on breast tissue in transgender patients: a concise review
yes
2/1/2020
4/20/2020
Breast Cancer Screening, Management, and a Review of Case Study Literature in Transgender Populations
Yes
9/1/2017
4/20/2020
Breast cancer and its impact in male transsexuals
No
7/5/2018
4/20/2020
Ovarian and endometrial cancer considerations in transgender men
No
6/17/2016
4/20/2020
Breast Cancer in Transgender Patients: A Systematic Review. Part 1: Male to Female
Yes
7/1/2018
4/20/2020
Breast Cancer in Transgender Patients: A Systematic Review. Part 2: Female to Male
Yes
7/1/2018
4/20/2020
Interdisciplinary Management of Transgender Individuals at Risk for Breast Cancer: Case Reports and Review of the Literature.
No
11/13/2018
4/20/2020
Breast cancer risk in transgender people receiving hormone treatment: nationwide cohort study in the Netherlands
No
5/14/2019
4/20/2020

CHRONIC ILLNESS

Title
Paywall
Date published
Date Added
Fibromuscular dysplasia in a middle-aged transgender man: The role of hormones in disease pathogenesis
No
6/14/2021
9/21/2022
Insulin resistance in transgender individuals correlates with android fat mass
No
1/23/2021
9/21/2022
Estrogen May Enhance Toll-Like Receptor 4-Induced Inflammatory Pathways in People With HIV: Implications for Transgender Women on Hormone Therapy
No
6/3/2022
9/21/2022
Idiopathic intracranial hypertension in a pediatric transgender patient
No
12/1/2021
9/21/2022
Assessment of Renal Function in Transgender Patients With Kidney Disease
No
6/4/2021
9/21/2022
Significant symptomatic improvement of subacute cutaneous lupus after testosterone therapy in a female-to-male transgender subject
Yes
10/9/2017
4/26/2020
Estrogen Reverses HDAC Inhibitor-Mediated Repression of Aicda and Class-Switching in Antibody and Autoantibody Responses by Downregulation of miR-26a
No
3/24/2020
4/21/2020
Development of systemic lupus erythematosus in a male-to-female transsexual: the role of sex hormones revisited
Yes
7/29/2013
4/21/2020
New onset systemic lupus erythematosus in a transgender man: possible role of feminizing sex hormones.
Yes
1/31/2007
4/21/2020
Effects of Sex Hormone Treatment on the Metabolic Syndrome in Transgender Individuals: Focus on Metabolic Cytokines
No
12/5/2017
4/20/2020
Sympathovagal imbalance in transsexual subjects
No
11/1/2008
4/20/2020
Feminization of chronic alcoholic men: a formulation.
No
3/1/1979
4/20/2020
Caring for transgender patients with epilepsy
No
8/3/2017
4/20/2020
Kallmann's syndrome and transsexualism
Yes
2/1/2001
4/20/2020
Endometriosis Presenting in a Transgender Male
Yes
11/1/2017
4/20/2020
Pelvic pain and persistent menses in transgender men
No
6/17/2016
4/20/2020
Immune Modulation And Increased Neurotrophic Factor Production In Multiple Sclerosis Patients Treated With Testosterone
No
7/31/2008
4/20/2020
Elevated Testosterone is Associated with Decreased Likelihood of Current Asthma Regardless of Gender
No
2/1/2019
4/20/2020
The role of testosterone in MS risk and course
No
1/8/2018
4/20/2020
Do low testosterone levels contribute to the pathogenesis of asthma?
No
6/26/2010
4/20/2020
Gender-Related Effects of Sex Steroids on Histamine Release and FcεRI Expression in Rat Peritoneal Mast Cells
No
4/20/2015
4/20/2020
Human mast cells express androgen receptors but treatment with testosterone exerts no influence on IgE‐independent mast cell degranulation elicited by neuromuscular blocking agents
No
2/11/2010
4/20/2020
Testosterone exerts selective anti‐inflammatory effects on human skin mast cells in a cell subset dependent manner
No
8/14/2012
4/20/2020
Female Sex Hormones Pattern and Its Relation to Disease Severity and Treatment in Pre- and Postmenopausal Patients with Chronic Hepatitis C Virus (Genotype 4) Infection
No
8/17/2015
4/20/2020
Novel associations between sex hormones and diabetic vascular complications in men and postmenopausal women: a cross-sectional study
No
7/31/2019
4/20/2020
Sex hormones and their influence on chronic kidney disease
No
1/1/2019
4/20/2020
Treatment of pain in fibromyalgia patients with testosterone gel: Pharmacokinetics and clinical response
No
8/1/2015
4/20/2020
Daily fluctuations of progesterone and testosterone are associated with fibromyalgia pain severity
No
12/14/2017
4/20/2020
ffects of gender-affirming hormone therapy on insulin resistance and body composition in transgender individuals: A systematic review
No
3/15/2020
4/20/2020
Development of systemic sclerosis in transgender females: a case series and review of the literature
No
2/19/2018
4/20/2020

DYSPHORIA

FERTILITY

GENERAL

Title
Paywall
Date published
Date Added
Biochemical Changes During the First Year of Feminizing Hormone Therapy in Transfeminine Individuals
No
2/1/2022
9/21/2022
Low estrogen doses normalize testosterone and estradiol levels to the female range in transgender women
No
5/1/2018
9/21/2022
Testosterone in men with hypogonadism and transgender males: a systematic review comparing three different preparations
No
7/25/2022
9/21/2022
A Stroke Case Associated with Tibolone Intake in a Male-to-Female Transgender Patient: A Case Report and Review of Literature
No
12/1/2021
9/21/2022
Effects of testosterone treatment on transgender males: A single-institution study
No
10/10/2021
9/21/2022
Optimal injection interval for testosterone undecanoate treatment of hypogonadal and transgender men
No
7/14/2021
9/21/2022
Medical management of transgender children and adolescents
No
12/7/2018
4/20/2020
Factors Associated with Gender-Affirming Surgery and Age of Hormone Therapy Initiation Among Transgender Adults
No
10/1/2017
4/20/2020
Clinical pearls of gender-affirming hormone therapy in transgender patients
No
3/26/2018
4/20/2020
Comparing the health of non-binary and binary transgender adults in a statewide non-probability sample
No
8/27/2019
4/20/2020
Health of Non-binary and Genderqueer People: A Systematic Review
No
6/25/2019
4/20/2020
Genders and Individual Treatment Progress in (Non-)Binary Trans Individuals
No
1/1/2018
4/20/2020
How Gender Identity and Treatment Progress Impact Decision-Making, Psychotherapy and Aftercare Desires of Trans Persons
No
5/26/2019
4/20/2020
Research Priorities for Gender Nonconforming/Transgender Youth: Gender Identity Development and Biopsychosocial Outcomes
No
4/1/2017
4/20/2020
A review of the physical and metabolic effects of cross-sex hormonal therapy in the treatment of gender dysphoria
No
5/1/2015
4/20/2020
Adult Development and Quality of Life of Transgender and Gender Nonconforming People
No
4/1/2017
4/20/2020
A Cross-Sectional Multicenter Study of Multidimensional Body Image in Adolescents and Adults with Gender Dysphoria Before and After Transition-Related Medical Interventions
No
8/7/2018
4/20/2020
Endocrinology of Transgender Medicine
No
10/10/2018
4/20/2020
Endocrine care of transpeople Part I. a review of cross-sex hormonal treatments, outcomes and adverse effects in transmen
Yes
2/1/2015
4/20/2020
Endocrine care of transpeople part II. A review of cross‐sex hormonal treatments, outcomes and adverse effects in transwomen
yes
2/18/2015
4/20/2020
ESTROGEN LEVELS DO NOT RISE WITH TESTOSTERONE TREATMENT FOR TRANSGENDER MEN
yes
3/20/2018
4/20/2020
PROLACTIN LEVELS DO NOT RISE AMONG TRANSGENDER WOMEN TREATED WITH ESTRADIOL AND SPIRONOLACTONE
yes
4/30/2018
4/20/2020
Increase in insuline-like growh factor levels during cross-sex hormone treatment in transgender persons
Yes
5/1/2016
4/20/2020
Testosterone undecanoate and testosterone enanthate injections are both effective and safe in transmen over 5 years of administration.
Yes
8/12/2018
4/20/2020
Long-Term Administration of Testosterone Undecanoate Every 3 Months for Testosterone Supplementation in Female-to-Male Transsexuals
No
9/1/2007
4/20/2020
(Patho)physiology of cross-sex hormone administration to transsexual people: The potential impact of male-female genetic differences
Yes
12/1/2014
4/20/2020
Brain Sex Differences Related to Gender Identity Development: Genes or Hormones?
No
3/19/2020
4/20/2020
Testosterone Effects on the Brain in Transgender Men.
No
5/1/2018
4/20/2020

GYNECOLOGICAL

Title
Paywall
Date published
Date Added
THE SEXUAL FUNCTION OF TRANSGENDER PEOPLE
No
6/1/2022
9/21/2022
The Effect of Gender-Affirming Medical Care on the Vaginal and Neovaginal Microbiomes of Transgender and Gender-Diverse People
No
1/21/2022
9/21/2022
Serum Levels of Sex Hormones in Vulvar Lichen Sclerosus, and the Effect of Topical Testosterone
Yes
2/23/1984
4/21/2020
OR11-3 Evidence for Preserved Ovarian Reserve in Transgender Men Receiving Testosterone Therapy: Anti-Mullerian Hormone Serum Levels Decrease Modestly after One Year of Treatment
Yes
4/30/2019
4/20/2020
Gynaecological aspects of the treatment and follow-up of transsexual men and women
No
3/1/2010
4/20/2020
Endometriosis Presenting in a Transgender Male
Yes
11/1/2017
4/20/2020
Impact of Exogenous Testosterone on Reproduction in Transgender Men
Yes
3/1/2020
4/20/2020
Uterine and ovarian changes during testosterone administration in young female-to-male transsexuals
No
10/1/2016
4/20/2020
Contraception Care for Transmasculine Individuals on Testosterone Therapy
yes
4/17/2019
4/20/2020
Contraception Across the Transmasculine Spectrum
No
8/1/2019
4/20/2020
Effects of long-term high dose testosterone administration on vaginal epithelium structure and estrogen receptor-α and -β expression of young women
No
4/4/2013
4/20/2020
Effect of Long-Term Testosterone Administration on the Endometrium of Female-to-Male (FtM) Transsexuals
Yes
7/1/2009
4/20/2020
Induction and Maintenance of Amenorrhea in Transmasculine and Nonbinary Adolescents
no
11/1/2017
4/20/2020
Pelvic pain and persistent menses in transgender men
No
6/17/2016
4/20/2020
Exogenous testosterone does not induce or exacerbate the metabolic features associated with pcos among transgender men
Yes
4/1/2018
4/20/2020
Uterine pathology in transmasculine persons on testosterone: a retrospective multicenter case series
No
3/1/2019
4/20/2020

HAIR & SKIN

Title
Paywall
Date published
Date Added
Angiofibroma stimulation in a transgender person receiving gender-affirming testosterone
No
10/1/2020
9/21/2022
Mapping evidence on the effects of gender-affirming hormone therapy on the hard and soft tissues of the craniofacial complex in transgender people: a protocol for a scoping review
No
4/14/2021
9/21/2022
From Anatomical Modifications to Skin Quality: Case Series of Botulinum Toxin and Facial Fillers for Facial Feminization in Transgender Women
No
4/2/2022
9/21/2022
Proliferation of steatocystomas in 2 transgender men
No
8/1/2022
9/21/2022
The Effect of Masculinizing Hormone Therapy On Wound Healing in Sterilized Mice
No
6/1/2022
9/21/2022
Acne fulminans in a transgender boy after an increase in testosterone dosage
No
3/1/2022
9/21/2022
Androgens and hair growth
Yes
9/1/2008
4/26/2020
Significant symptomatic improvement of subacute cutaneous lupus after testosterone therapy in a female-to-male transgender subject
Yes
10/9/2017
4/26/2020
A randomized, double-blind, placebo-controlled study on the effect of conjugated estrogens on skin thickness.
Yes
2/1/1994
4/21/2020
Antiandrogen therapy for skin and hair disease.
Yes
4/1/2006
4/21/2020
Serum Levels of Sex Hormones in Vulvar Lichen Sclerosus, and the Effect of Topical Testosterone
Yes
2/23/1984
4/21/2020
Estrogens and the hair follicle.
Yes
6/1/2004
4/21/2020
Development of systemic lupus erythematosus in a male-to-female transsexual: the role of sex hormones revisited
Yes
7/29/2013
4/21/2020
Risk factors for genital lichen sclerosus in men
Yes
10/1/2010
4/21/2020
Hair regrowth in a male patient with extensive androgenetic alopecia on estrogen therapy
Yes
9/1/2012
4/21/2020
Medical dermatologic conditions in transgender women
No
10/11/2018
4/21/2020
New onset systemic lupus erythematosus in a transgender man: possible role of feminizing sex hormones.
Yes
1/31/2007
4/21/2020
Risk factors for acne development in the first 2 years after initiating masculinizing testosterone therapy among transgender men
No
8/1/2019
4/21/2020
Short- and Long-Term Clinical Skin Effects of Testosterone Treatment in Trans Men
No
10/31/2013
4/21/2020
Estrogens and aging skin
No
4/1/2013
4/21/2020
Scalp Hair Regrowth in Hormone-Treated Transgender Woman
No
10/1/2016
4/21/2020
Effects of Sex Steroid Deprivation/Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females
no
8/1/2000
4/20/2020
Severe Acne in Female-to-Male Transgender Patients
no
11/1/2015
4/20/2020
Dermatologic Conditions in Transgender Populations
Yes
6/1/2019
4/20/2020

HEART & VASCULAR HEALTH

Title
Paywall
Date published
Date Added
Insulin resistance in transgender individuals correlates with android fat mass
No
1/23/2021
9/21/2022
Masculinising testosterone treatment and effects on preclinical cardiovascular disease, muscle strength and power, aggression, physical fitness and respiratory function in transgender men: protocol for a 10-year, prospective, observational cohort study in Denmark at the Body Identity Clinic (BIC)
No
12/1/2020
9/21/2022
Risk of Venous Thromboembolism in Transgender People Undergoing Hormone Feminizing Therapy: A Prevalence Meta-Analysis and Meta-Regression Study
No
11/9/2021
9/21/2022
Effects of testosterone treatment on transgender males: A single-institution study
No
10/10/2021
9/21/2022
Malignant cerebral venous thrombosis in a transgender patient: intraoperative aspect of vein of Trolard thrombosis
No
10/1/2021
9/21/2022
Feminizing Hormone Therapy Prescription Patterns and Cardiovascular Risk Factors in Aging Transgender Individuals in Australia
No
7/13/2021
9/21/2022
The Relationship Between Tobacco Use and Legal Document Gender-Marker Change, Hormone Use, and Gender-Affirming Surgery in a United States Sample of Trans-Feminine and Trans-Masculine Individuals: Implications for Cardiovascular Health
No
10/1/2018
4/20/2020
Transwomen and the Metabolic Syndrome: Is Orchiectomy Protective?
No
8/1/2016
4/20/2020
Gender-Affirming Hormone Therapy, Vascular Health and Cardiovascular Disease in Transgender Adults
No
10/28/2019
4/20/2020
Effects of Sex Hormone Treatment on the Metabolic Syndrome in Transgender Individuals: Focus on Metabolic Cytokines
No
12/5/2017
4/20/2020
Prevalence of cardiovascular disease and cancer during cross-sex hormone therapy in a large cohort of trans persons: a case–control study
No
9/13/2013
4/20/2020
Vascular reactivity is impaired in genetic females taking high-dose androgens
No
11/1/1998
4/20/2020
Sympathovagal imbalance in transsexual subjects
No
11/1/2008
4/20/2020
Cardiovascular disease in transgendered people: A review of the literature and discussion of risk
No
9/30/2019
4/20/2020
Cardiovascular Implications of Gender-Affirming Hormone Treatment in the Transgender Population
No
8/1/2019
4/20/2020
Surgical and pharmacological reassignment: influence on transsexual cardiovascular risk profile
Yes
8/1/2017
4/20/2020
Novel associations between sex hormones and diabetic vascular complications in men and postmenopausal women: a cross-sectional study
No
7/31/2019
4/20/2020

HIV & PREP

Title
Paywall
Date published
Date Added
Longitudinal Cohort Study of Gender Affirmation and HIV-Related Health in Transgender and Gender Diverse Adults: The LEGACY Project Protocol
No
3/1/2021
9/21/2022
Effects of Gender-Affirming Hormone Therapy on Progression Along the HIV Care Continuum in Transgender Women
No
12/1/2021
9/21/2022
Decreased Tenofovir Diphosphate Concentrations in a Transgender Female Cohort: Implications for Human Immunodeficiency Virus Preexposure Prophylaxis
No
12/15/2019
9/21/2022
Drug‐drug interactions between feminizing hormone therapy and pre‐exposure prophylaxis among transgender women: the iFACT study
No
7/1/2019
9/21/2022
Drug-drug Interactions Among Thai Transgender Women Living with Human Immunodeficiency Undergoing Feminizing Hormone Therapy and Antiretroviral Therapy: The iFACT Study
No
2/1/2021
9/21/2022
Transgender women on oral HIV pre‐exposure prophylaxis have significantly lower tenofovir and emtricitabine concentrations when also taking oestrogen when compared to cisgender men
No
11/1/2019
9/21/2022
Sex Hormone Therapy and Tenofovir Diphosphate Concentration in Dried Blood Spots: Primary Results of the Interactions Between Antiretrovirals And Transgender Hormones Study
Yes
8/8/2020
9/21/2022
Gender-Affirming Hormone Pharmacokinetics Among Adolescent and Young Adult Transgender Persons Receiving Daily Emtricitabine/Tenofovir Disoproxil Fumarate
Yes
8/29/2022
9/21/2022
Estrogen May Enhance Toll-Like Receptor 4-Induced Inflammatory Pathways in People With HIV: Implications for Transgender Women on Hormone Therapy
No
6/3/2022
9/21/2022

LONG TERM

MENTAL HEALTH

Title
Paywall
Date published
Date Added
Physical and Psychological Effects of Gender-Affirming Hormonal Treatment Using Intramuscular Testosterone Enanthate in Japanese Transgender Men
No
4/1/2021
9/21/2022
Short-Term Effects of Gender-Affirming Hormone Therapy on Dysphoria and Quality of Life in Transgender Individuals: A Prospective Controlled Study
No
7/29/2021
9/21/2022
Effects of low-dose oral micronised progesterone on sleep, psychological distress, and breast development in transgender individuals undergoing feminising hormone therapy: a prospective controlled study
No
5/23/2022
9/21/2022
Access to gender-affirming hormones during adolescence and mental health outcomes among transgender adults
No
1/12/2022
9/21/2022
Pubertal Suppression for Transgender Youth and Risk of Suicidal Ideation
No
2/1/2020
4/20/2020
A Role for Estrogen in Schizophrenia: Clinical and Preclinical Findings
No
9/27/2015
4/20/2020
Progesterone: The neglected hormone in schizophrenia? A focus on progesterone-dopamine interactions.
No
8/24/2016
4/20/2020
Estradiol reverses excitatory synapse loss in a cellular model of neuropsychiatric disorders
No
1/21/2020
4/20/2020
Sex differences in schizophrenia, bipolar disorder, and post-traumatic stress disorder: Are gonadal hormones the link?
No
3/14/2019
4/20/2020
Aggression: The Testosterone-Serotonin Link
No
9/1/2003
4/20/2020
Correlates of suicide ideation and behaviors among transgender people: A systematic review guided by ideation-to-action theory
No
6/21/2018
4/20/2020
Hormone-treated transsexuals report less social distress, anxiety and depression
No
8/23/2011
4/20/2020
A Systematic Review of the Effects of Hormone Therapy on Psychological Functioning and Quality of Life in Transgender Individuals
No
1/1/2016
4/20/2020
High-Dose Testosterone Treatment Increases Serotonin Transporter Binding in Transgender People
No
9/1/2014
4/20/2020
Testosterone levels in suicide attempters with bipolar disorder
No
10/29/2013
4/20/2020
Sex hormones play a role in vulnerability to sleep loss on emotion processing tasks
No
10/12/2017
4/20/2020
Testosterone as a biological marker in psychopathy and alcoholism
No
11/21/1997
4/20/2020
Gender-Affirming Hormone Use in Transgender Individuals: Impact on Behavioral Health and Cognition
No
10/11/2018
4/20/2020
Cognitive Impacts of Estrogen Treatment in Androgen-Deprived Males: What Needs to be Resolved
No
3/1/2017
4/20/2020
How Gender Identity and Treatment Progress Impact Decision-Making, Psychotherapy and Aftercare Desires of Trans Persons
No
5/26/2019
4/20/2020

NON-BINARY

PAIN

PHYSICAL CHANGES

Title
Paywall
Date published
Date Added
Physical and Psychological Effects of Gender-Affirming Hormonal Treatment Using Intramuscular Testosterone Enanthate in Japanese Transgender Men
No
4/1/2021
9/21/2022
Testosterone therapy masculinizes speech and gender presentation in transgender men
No
2/10/2021
9/21/2022
Masculinising testosterone treatment and effects on preclinical cardiovascular disease, muscle strength and power, aggression, physical fitness and respiratory function in transgender men: protocol for a 10-year, prospective, observational cohort study in Denmark at the Body Identity Clinic (BIC)
No
12/1/2020
9/21/2022
Mapping evidence on the effects of gender-affirming hormone therapy on the hard and soft tissues of the craniofacial complex in transgender people: a protocol for a scoping review
No
4/14/2021
9/21/2022
Examining Chest Femininity of Hormone Treated Vs. Surgically Augmented Transgender Women
No
6/1/2022
9/21/2022
Effects of low-dose oral micronised progesterone on sleep, psychological distress, and breast development in transgender individuals undergoing feminising hormone therapy: a prospective controlled study
No
5/23/2022
9/21/2022
COMPARISON OF CHEST FEMININITY OF TRANSGENDER WOMEN WITH HORMONE TREATMENT VS. SURGICALLY AUGMENTED WITH BREAST IMPLANTS
No
4/1/2022
9/21/2022
Clitoral Priapism in a Transgender Male
No
12/1/2021
9/21/2022
Can exogenous oestrogen in transitioning transgender females increase incidence of fibroadenomata?
No
12/1/2021
9/21/2022
Gynecomastia in a Transgender Boy: A Case Report
No
12/1/2021
9/21/2022
Res Ipsa - Testicular histology after feminizing hormone therapy
No
11/1/2021
9/21/2022
Breast Development in Transwomen After 1 Year of Cross-Sex Hormone Therapy: Results of a Prospective Multicenter Study
No
11/20/2017
4/20/2020
Effectiveness of testosterone therapy for masculinizing voice in transgender patients: A meta-analytic review
No
3/13/2018
4/20/2020
Effects of hormones and hormone therapy on breast tissue in transgender patients: a concise review
yes
2/1/2020
4/20/2020
Effects of testosterone therapy on BMI, blood pressure, and laboratory profile of transgender men: a systematic review.
No
7/14/2017
4/20/2020
Voice deepening under testosterone treatment in female-to-male gender dysphoric individuals
Yes
12/1/2015
4/20/2020
OR11-3 Evidence for Preserved Ovarian Reserve in Transgender Men Receiving Testosterone Therapy: Anti-Mullerian Hormone Serum Levels Decrease Modestly after One Year of Treatment
Yes
4/30/2019
4/20/2020
Effect of Long-Term Administration of Cross-Sex Hormone Therapy on Serum and Urinary Uric Acid in Transsexual Persons
No
6/1/2008
4/20/2020
Sex Hormones and Inner Ear
No
5/2/2018
4/20/2020
The ovarian hormone estradiol plays a crucial role in the control of food intake in females
No
9/26/2011
4/20/2020
Body composition, bone turnover, and bone mass in trans men during testosterone treatment: 1-year follow-up data from a prospective case–controlled study (ENIGI)
No
2/1/2015
4/20/2020

SEX

Title
Paywall
Date published
Date Added
THE SEXUAL FUNCTION OF TRANSGENDER PEOPLE
No
6/1/2022
9/21/2022
A Proposed Inventory to Assess Changes in Orgasm Function of Transgender Patients Following Gender Affirming Treatments: Pilot Study
No
6/1/2022
9/21/2022
Sexual Functioning in Transsexuals Following Hormone Therapy and Genital Surgery: A Review (CME)
No
11/01/2009
4/20/2020
Sexual and Physical Health After Sex Reassignment Surgery
No
12/1/2005
4/20/2020
Sexual Desire in Trans Persons: Associations with SexReassignment Treatment
No
1/1/2014
4/20/2020
A Prospective Study on Sexual Function and Mood in Female-to-Male Transsexuals During Testosterone Administration and After Sex Reassignment Surgery
No
3/7/2013
4/20/2020
Gynaecological aspects of the treatment and follow-up of transsexual men and women
No
3/1/2010
4/20/2020
Sexual desire in female-to-male transsexual persons: exploration of the role of testosterone administration
No
5/20/2011
4/20/2020
Effects of transdermal testosterone or oral dydrogesterone on hypoactive sexual desire disorder in transsexual women: results of a pilot study.
Yes
6/4/2009
4/20/2020
Hypoactive sexual desire in transsexual women: prevalence and association with testosterone levels.
Yes
3/1/2008
4/20/2020
Transsexuals and Sexual Health
No
11/1/2009
4/20/2020
The effects of androgen depletion on human erectile function: a prospective study in male-to-female transsexuals
no
6/3/2004
4/20/2020
Orgasm in the postoperative transsexual
Yes
4/1/1993
4/20/2020
Long-Term Sensitivity and Patient-Reported Functionality of the Neoclitoris After Gender Reassignment Surgery
Yes
2/1/2017
4/20/2020

SLEEP

SUBSTANCE USE/ABUSE

Title
Paywall
Date published
Date Added
Females Are More Vulnerable to Drug Abuse than Males: Evidence from Preclinical Studies and the Role of Ovarian Hormones
Yes
1/1/2011
4/26/2020
Ovarian hormones and propensity to drug relapse: A review
Yes
1/1/2011
4/26/2020
Sex differences in the vulnerability to drug abuse: a review of preclinical studies
Yes
10/1/2004
4/26/2020
Sex Differences in Drug Addiction: A Review of Animal and Human Studies
No
1/1/2008
4/26/2020
Biological basis of sex differences in drug abuse: preclinical and clinical studies
No
9/5/2002
4/26/2020
Ovarian Hormones and Drug Abuse
No
11/1/2014
4/26/2020
Sex hormones in alcohol consumption: a systematic review of evidence
No
12/27/2017
4/20/2020
The Relationship Between Tobacco Use and Legal Document Gender-Marker Change, Hormone Use, and Gender-Affirming Surgery in a United States Sample of Trans-Feminine and Trans-Masculine Individuals: Implications for Cardiovascular Health
No
10/1/2018
4/20/2020
Testosterone as a biological marker in psychopathy and alcoholism
No
11/21/1997
4/20/2020
The role of testosterone in the development of experimental alcoholism
No
1/1/1980
4/20/2020
CONTROLLED STUDY ON THE COMBINED EFFECT OF ALCOHOL AND TOBACCO SMOKING ON TESTOSTERONE IN ALCOHOL-DEPENDENT MEN
No
10/17/2006
4/20/2020
Feminization of chronic alcoholic men: a formulation.
No
3/1/1979
4/20/2020
Correlations between sex-related hormones, alcohol dependence and alcohol craving.
No
4/1/2019
4/20/2020
Association of testosterone and BDNF serum levels with craving during alcohol withdrawal
No
8/1/2016
4/20/2020

YOUTH

Title
Paywall
Date published
Date Added
Access to gender-affirming hormones during adolescence and mental health outcomes among transgender adults
No
1/12/2022
9/21/2022
Idiopathic intracranial hypertension in a pediatric transgender patient
No
12/1/2021
9/21/2022
Gynecomastia in a Transgender Boy: A Case Report
No
12/1/2021
9/21/2022
Beyond the Binary: Sexual and Reproductive Health Considerations for Transgender and Gender Expansive Adolescents
No
10/6/2021
9/21/2022
Medical management of transgender children and adolescents
No
12/7/2018
4/20/2020
Gender-affirming hormones and surgery in transgender children and adolescents
No
6/1/2019
4/20/2020
Pubertal Suppression for Transgender Youth and Risk of Suicidal Ideation
No
2/1/2020
4/20/2020
Effect of pubertal suppression and cross-sex hormone therapy on bone turnover markers and bone mineral apparent density (BMAD) in transgender adolescents
No
11/11/2016
4/20/2020
Puberty suppression in transgender children and adolescents
No
10/1/2017
4/20/2020
Bone Mass in Young Adulthood Following Gonadotropin-Releasing Hormone Analog Treatment and Cross-Sex Hormone Treatment in Adolescents With Gender Dysphoria
No
2/1/2015
4/20/2020
Puberty suppression and executive functioning: An fMRI-study in adolescents with gender dysphoria
No
3/1/2015
4/20/2020
Male-typical visuospatial functioning in gynephilic girls with gender dysphoria — Organizational and activational effects of testosterone
No
4/1/2016
4/20/2020
Gonadal Suppressive and Cross-Sex Hormone Therapy for Gender Dysphoria in Adolescents and Adults
Yes
12/1/2014
4/20/2020
Research Priorities for Gender Nonconforming/Transgender Youth: Gender Identity Development and Biopsychosocial Outcomes
No
4/1/2017
4/20/2020
Endocrine care of transpeople Part I. a review of cross-sex hormonal treatments, outcomes and adverse effects in transmen
Yes
2/1/2015
4/20/2020
Endocrine care of transpeople part II. A review of cross‐sex hormonal treatments, outcomes and adverse effects in transwomen
yes
2/18/2015
4/20/2020
Induction and Maintenance of Amenorrhea in Transmasculine and Nonbinary Adolescents
no
11/1/2017
4/20/2020